Investigating the Human Genome (PATRICIA BLAIR's Library) by Moyra Smith
Author:Moyra Smith
Language: eng
Format: epub
Publisher: FT Press
Published: 2010-06-23T16:00:00+00:00
Molecular-based treatment design in Alzheimer’s disease
Neprilysin is an endopeptidase that is expressed in a number of different tissues, including the brain. Studies on mouse tissues revealed that tissue-specific transcripts are generated and that transcripts in neurons, oligodendrocytes, and kidneys each differ with respect to the exons they contain (Iwata, et al., 2001). Studies on mice hemizygous for neprilysin deficiency revealed increased brain amyloid Abeta42 levels. Evidence also indicates that neprilysin levels are decreased in Alzheimer’s disease and that neprilysin levels are negatively correlated with amyloid levels. Wang, et al. (2010), proposed that measures that increase neprilysin levels might constitute a pathway to Alzheimer’s disease treatment.
Download
This site does not store any files on its server. We only index and link to content provided by other sites. Please contact the content providers to delete copyright contents if any and email us, we'll remove relevant links or contents immediately.
Anatomy | Bacteriology |
Biochemistry | Biostatistics |
Biotechnology | Cell Biology |
Embryology | Epidemiology |
Genetics | Histology |
Immunology | Microbiology |
Neuroanatomy | Nosology |
Pathophysiology | Physiology |
Virology |
Tuesdays with Morrie by Mitch Albom(4369)
Yoga Anatomy by Kaminoff Leslie(4092)
Science and Development of Muscle Hypertrophy by Brad Schoenfeld(3958)
Bodyweight Strength Training: 12 Weeks to Build Muscle and Burn Fat by Jay Cardiello(3764)
Introduction to Kinesiology by Shirl J. Hoffman(3607)
How Music Works by David Byrne(2942)
Sapiens and Homo Deus by Yuval Noah Harari(2823)
The Plant Paradox by Dr. Steven R. Gundry M.D(2404)
Insomniac City by Bill Hayes(2381)
Coroner's Journal by Louis Cataldie(2349)
Churchill by Paul Johnson(2341)
The Chimp Paradox by Peters Dr Steve(2204)
Hashimoto's Protocol by Izabella Wentz PharmD(2184)
The Universe Inside You by Brian Clegg(2037)
The Immune System Recovery Plan by Susan Blum(1951)
Don't Look Behind You by Lois Duncan(1904)
The Hot Zone by Richard Preston(1893)
Endure by Alex Hutchinson(1854)
Woman: An Intimate Geography by Natalie Angier(1833)
